Mentalization-based treatment versus bona fide treatment for patients with borderline personality disorder in Germany (MAGNET): study protocol of a prospective, multi-centre randomized controlled trial

Borderline Personality Disorder (BPD) is a serious mental disorder. Mentalization-based treatment (MBT) is an evidence-based treatment for individuals with BPD. Specifically, MBT has previously been highlighted for its effectiveness regarding the reduction of suicidal and non-suicidal self-injury (N...

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Hauptverfasser: Hauschild, Sophie (VerfasserIn) , Taubner, Svenja (VerfasserIn) , Vidalón Blachowiak, Thorsten (VerfasserIn) , Dinger, Ulrike (VerfasserIn) , Gündel, Harald (VerfasserIn) , Herpertz, Sabine (VerfasserIn) , Rademacher, Jörg (VerfasserIn) , Strauss, Bernhard (VerfasserIn) , Storck, Timo (VerfasserIn) , Vassileva, Ralitsa (VerfasserIn) , Burghaus, Ina (VerfasserIn) , Herbst, Manuel (VerfasserIn) , Chen, Simiao (VerfasserIn) , Nikendei, Christoph (VerfasserIn) , Euler, Sebastian (VerfasserIn) , Volkert, Jana (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 11 April 2025
In: BMC psychiatry
Year: 2025, Jahrgang: 25, Pages: 1-19
ISSN:1471-244X
DOI:10.1186/s12888-025-06809-0
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12888-025-06809-0
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Verfasserangaben:Sophie Hauschild, Svenja Taubner, Thorsten Vidalón Blachowiak, Ulrike Dinger, Harald Gündel, Sabine C. Herpertz, Jörg Rademacher, Bernhard Strauss, Timo Storck, Ralitsa Vassileva, Ina Burghaus, Manuel Herbst, Simiao Chen, Christoph Nikendei, Sebastian Euler and Jana Volkert
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Zusammenfassung:Borderline Personality Disorder (BPD) is a serious mental disorder. Mentalization-based treatment (MBT) is an evidence-based treatment for individuals with BPD. Specifically, MBT has previously been highlighted for its effectiveness regarding the reduction of suicidal and non-suicidal self-injury (NSSI). Yet, randomized-controlled trials (RCT) on MBT in outpatient settings compared with bona fide treatment (BFT) are still scarce and none has been conducted in Germany. The primary objective of this RCT is to investigate whether outpatient MBT is more effective in the reduction of crisis events (incidences of NSSI and suicide attempts) compared with BFT (namely psychodynamic or cognitive-behavioural psychotherapy) in Germany. Secondary, MBT’s efficacy will be investigated with regard to cost-effectiveness within the German health care system, general and interpersonal functioning, BPD and general symptom severity, social adjustment, quality of life, reduction in psychotropic medication and therapy retention. Additionally, moderator as well as common and treatment specific mediator variables will be investigated.
Beschreibung:Gesehen am 08.10.2025
Beschreibung:Online Resource
ISSN:1471-244X
DOI:10.1186/s12888-025-06809-0