Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma

The prognosis of multiple myeloma patients varies widely. Here, to identify genetic factors associated with differing prognoses, the authors carried out a meta-analysis of four genome-wide association studies and identified a risk variant associated with survival interval.

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Bibliographic Details
Main Authors: Johnson, David C. (Author) , Weinhold, Niels (Author) , Mitchell, Jonathan S. (Author) , Chen, Bowang (Author) , Kaiser, Martin (Author) , Begum, Dil B. (Author) , Hillengaß, Jens (Author) , Bertsch, Uta (Author) , Gregory, Walter A. (Author) , Cairns, David (Author) , Jackson, Graham H. (Author) , Försti, Asta (Author) , Nickel, Jolanta (Author) , Hoffmann, Per (Author) , Nöethen, Markus M. (Author) , Stephens, Owen W. (Author) , Barlogie, Bart (Author) , Davis, Faith E. (Author) , Hemminki, Kari (Author) , Goldschmidt, Hartmut (Author) , Houlston, Richard S. (Author) , Morgan, Gareth J. (Author)
Format: Article (Journal)
Language:English
Published: 8 Jan 2016
In: Nature Communications
Year: 2016, Volume: 7, Pages: 1-7
ISSN:2041-1723
DOI:10.1038/ncomms10290
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ncomms10290
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ncomms10290
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Author Notes:David C. Johnson, Niels Weinhold, Jonathan S. Mitchell, Bowang Chen, Martin Kaiser, Dil B. Begum, Jens Hillengass, Uta Bertsch, Walter A. Gregory, David Cairns, Graham H. Jackson, Asta Försti, Jolanta Nickel, Per Hoffmann, Markus M. Nöethen, Owen W. Stephens, Bart Barlogie, Faith E. Davis, Kari Hemminki, Hartmut Goldschmidt, Richard S. Houlston & Gareth J. Morgan
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Summary:The prognosis of multiple myeloma patients varies widely. Here, to identify genetic factors associated with differing prognoses, the authors carried out a meta-analysis of four genome-wide association studies and identified a risk variant associated with survival interval.
Item Description:Gesehen am 06.05.2020
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/ncomms10290