The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

Richard Houlston, Kari Hemminki and colleagues report a meta-analysis of genome-wide association studies of multiple myeloma and identify a variant in the CCDN1 gene that influences risk for developing a specific tumor karyotype with the t(11;14)(q13;q32) translocation.

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Main Authors: Weinhold, Niels (Author) , Johnson, David C. (Author) , Chubb, Daniel (Author) , Chen, Bowang (Author) , Försti, Asta (Author) , Hosking, Fay J. (Author) , Broderick, Peter (Author) , Ma, Yussanne P. (Author) , Dobbins, Sara E. (Author) , Hose, Dirk (Author) , Walker, Brian A. (Author) , Davies, Faith E. (Author) , Kaiser, Martin F. (Author) , Li, Ni L. (Author) , Gregory, Walter A. (Author) , Jackson, Graham H. (Author) , Witzens-Harig, Mathias (Author) , Neben, Kai (Author) , Hoffmann, Per (Author) , Nöthen, Markus M. (Author) , Mühleisen, Thomas W. (Author) , Eisele, Lewin (Author) , Ross, Fiona M. (Author) , Jauch, Anna (Author) , Goldschmidt, Hartmut (Author) , Houlston, Richard S. (Author) , Morgan, Gareth J. (Author) , Hemminki, Kari (Author)
Format: Article (Journal) Editorial
Language:English
Published: 17 March 2013
In: Nature genetics
Year: 2013, Volume: 45, Issue: 5, Pages: 522-526
ISSN:1546-1718
DOI:10.1038/ng.2583
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ng.2583
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ng.2583
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Author Notes:Niels Weinhold, David C. Johnson, Daniel Chubb, Bowang Chen, Asta Försti, Fay J. Hosking, Peter Broderick, Yussanne P. Ma, Sara E. Dobbins, Dirk Hose, Brian A. Walker, Faith E. Davies, Martin F. Kaiser, Ni L. Li, Walter A. Gregory, Graham H. Jackson, Mathias Witzens-Harig, Kai Neben, Per Hoffmann, Markus M. Nöthen, Thomas W. Mühleisen, Lewin Eisele, Fiona M. Ross, Anna Jauch, Hartmut Goldschmidt, Richard S. Houlston, Gareth J. Morgan & Kari Hemminki
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Summary:Richard Houlston, Kari Hemminki and colleagues report a meta-analysis of genome-wide association studies of multiple myeloma and identify a variant in the CCDN1 gene that influences risk for developing a specific tumor karyotype with the t(11;14)(q13;q32) translocation.
Item Description:Gesehen am 28.10.2021
Physical Description:Online Resource
ISSN:1546-1718
DOI:10.1038/ng.2583